Author: Muhammad Imran Qadir, Atta Ur Rehman, Muhammad Sajid Hamid Akash, Muhammad Irfan, Muhammad Baber and Syed Bilal Hussain
Publishing Date: 2016
E-ISSN: 1011-601X
Volume 29 Issue 6
ABSTRACT:
Although aspirin-clopidogrel combination is more useful for acute coronary syndrome (ACS), the renal safety of this combination had not been established. A total 60 patients with ACS were divided into three groups; receiving aspirin, clopidogrel and aspirin-clopidogrel combination. For determination of renal function, serum BUN, creatinine, uric acid, uric acid clearance and GFR were estimated for four months. The study showed that there were no significant (p>0.05) variations in the parameters when used the drugs in combination (aspirin-clopidogrel) compared with the drugs given alone.
KEYWORDS: Aspirin-clopidogrel combination, renal function