Author: Saeed Ahmad, Fariha Rashid Bhatti, Farhan Hameed Khaliq, Tehreem Younas, Asadullah Madni and Abida Latif
Publishing Date: 2016
E-ISSN: 1011-601X
Volume: 29 Issue: 5
ABSTRACT:
The present study demonstrates the biological study of Ficus carica fruit. Methanolic extract of plant fruit was prepared and evaporated under reduced pressure by rota vapor and n- hexane, Chloroform, ethyl acetate and n-butanol soluble fractions were prepared separately from crude methanolic extract. These fractions were then screened for acetyl cholinesterase, butryl cholinesterase and lipoxygenase activities. n-butanol soluble fraction showed significant antiacetylcholinesterase activity (78.55±0.76%) with IC50 of 55.8±0.37μg/ml, ethyl acetate soluble fraction showed significant anti-butrylcholinesterase activity (70.35±0.85%) with IC50 of 276.5±0.64μg/ml and significant antilipoxygenase activity was shown by ethyl acetate soluble fraction (62.52±0.26%) with IC50 of 380±0.08μg/ml.
KEYWORDS: Ficus carica, anti-acetyl cholinesterase, butryl cholinesterase, lipoxygenase.